Construction Begins on Combined Sanford Health and Lewis Drug Site in Southeast Sioux Falls

October 28, 2026 - 02:00

Sanford Health has started construction on a combined clinic and Lewis Drug location in southeast Sioux Falls, marking the beginning of a project that will bring health care and pharmacy services together under one roof.

The new facility is designed to offer patients convenient access to primary care and retail pharmacy services in a single stop. Officials say the shared location reflects a growing trend toward integrating medical care with everyday health needs, making it easier for residents in the fast-growing southeast part of the city to see a provider and fill prescriptions without traveling across town.

Construction crews have begun site work, and the project is expected to take shape over the coming months. The building will include space for Sanford Health providers and staff as well as a full-service Lewis Drug store, which will carry household goods, over-the-counter medications and other retail items alongside prescription services.

Local leaders welcomed the development, noting that the southeast side has seen steady residential growth and needs more accessible services. The combined site is expected to create jobs during construction and permanent positions once it opens.

A timeline for completion has not been finalized, but company representatives say updates will be shared as the project progresses. Both organizations described the partnership as a practical way to serve a changing community and improve access to care close to home.